翻訳と辞書 Words near each other ・ Pirili, Çukurova ・ Pirillo ・ Pirilyar ・ Pirimela ・ Pirimi Pererika Tahiwi ・ Pirimicarb ・ Pirimiphos-methyl ・ Pirin ・ Pirin (village) ・ Pirin Folk Ensemble ・ Pirin Glacier ・ Pirin National Park ・ Pirin-Fiat ・ Piringsdorf ・ Pirinio ・ Pirinixic acid ・ Pirinsko Pivo ・ Pirinçlik Air Base ・ Piripi Taumata-a-Kura ・ Piripi Te Maari-o-te-rangi ・ Piripiri ・ Piripiri, Piauí ・ Piripucu River ・ Piripá ・ Piriri to Yukō! ・ Pirissi and Tulubri ・ Pirisudanol ・ Pirita ・ Pirita (disambiguation) ・ Pirita (river) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Pirinixic acid ： ウィキペディア英語版 Pirinixic acid Pirinixic acid is a peroxisome proliferator-activated receptor alpha (PPARα) agonist that is under experimental investigation for prevention of severe cardiac dysfunction, cardiomyopathy and heart failure as a result of lipid accumulation within cardiac myocytes. Treatment is primarily aimed at individuals with an adipose triglyceride lipase (ATGL) enzyme deficiency or mutation because of the essential PPAR protein interactions with free fatty acid monomers derived from the ATGL catalyzed lipid oxidation reaction. It was discovered as WY-14,643 in 1974. ==Adipose triglyceride lipase (ATGL)== Adipose triglyceride lipase (ATGL), an enzyme that catalyzes the rate limiting hydrolysis step of triglycerides in the triacylglycerol lipolysis cascade, is expressed predominantly in adipose tissue, but is also found in lesser amounts within cardiac and skeletal muscle. Its function is to initiate the breakdown of intracellular triglycerides into fatty acid monomers. Individuals deficient in the ATGL enzyme are at higher risk for cardiac dysfunction and premature death because of increased size and accumulation of lipid droplets within cardiac myocytes. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pirinixic acid」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.